品牌:美國(guó) NewEast Biosciences
貨號(hào): 26904
抗原:Full Recombinant active RhoA
規(guī)格:30 微升
產(chǎn)品全名:Anti-RhoA-GTP Mouse Monoclonal Antibody
應(yīng)用: IP, IHC, IF
種屬反應(yīng)性的選擇:Human, Mouse and Rat
物種/宿主:Mouse
描述: Anti-RhoA-GTP Mouse Monoclonal Antibody
背景介紹: Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell motility, contraction, and cytokinesis. It regulates the formation of stress fibers and focal adhesions in fibroblasts and Ca 2+ sensitivity of smooth muscle contraction.
免疫原: Recombinant full length protein of active RhoA
經(jīng)過(guò)測(cè)試的應(yīng)用: IP, IHC,IF
推薦稀釋比: IP: 1 μg for 1~2 mg total cellular proteins IHC, IF: 1:50-1:250
濃度: 1 mg/ml
宿主: Mouse
形式: Liquid
克隆性: Monoclonal
亞型: IgG2b
純度: Purified from ascites
防腐劑: No
成分: PBS (without Mg 2+ and Ca 2+ ), pH 7.4, 150 mM NaCl, 50% glycerol
種屬反應(yīng)性: Anti-RhoA monoclonal antibody recognizes active RhoA from vertebrates.
儲(chǔ)存條件: Store at -20°C. Avoid repeated freezing and thawing
Immunoprecipitation/Western Blot:
IP/WB Analysis of Active RhoA Protein.Purified recombinant RhoA proteins were loaded with GDP (lane 1) or GTPγS (lane 2). These proteins were immunoprecipitated with anti-RhoA-GTP monoclonal antibody (Cat. # 26904). After SDS/PAGE, the membrane filter was probed with anti-RhoA mouse monoclonal antibody (Cat. # 26007).
武漢費(fèi)斯德生物科技有限公司是美國(guó)NewEast Biosciences在中國(guó)的辦事處，也是目前所有產(chǎn)品國(guó)內(nèi)經(jīng)銷處。
目前客戶使用產(chǎn)品發(fā)表超過(guò)1000谷歌學(xué)術(shù)文獻(xiàn)，其中論文分布排名前50刊物上。
NewEast Biosciences 在十二年前率先研發(fā)倆種獨(dú)特的抗體。這倆種抗體僅僅識(shí)別活性的GTP酶或者突變的Oncogene。 GTP酶涉及(1)響應(yīng)細(xì)胞表面受體**的信號(hào)轉(zhuǎn)導(dǎo)，包括跨膜受體，例如介導(dǎo)味覺(jué)、嗅覺(jué)和視覺(jué)的那些，（2）核糖體的蛋白質(zhì)生物合成，（3）調(diào)節(jié)細(xì)胞分化、增殖、分裂和運(yùn)動(dòng)，（4）蛋白質(zhì)通過(guò)膜的易位，（5）細(xì)胞內(nèi)囊泡的運(yùn)輸，以及囊泡介導(dǎo)的分泌和攝取，通過(guò)GTP酶控制囊泡外殼組裝。Oncogene側(cè)是誘發(fā)癌癥的基因。
更多產(chǎn)品類目和技術(shù)資料可查看：武漢費(fèi)斯德生物官網(wǎng)。
